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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC1
All Species:
25.76
Human Site:
T445
Identified Species:
43.59
UniProt:
Q9NV70
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV70
NP_001020095.1
894
101982
T445
K
E
S
K
K
F
A
T
L
P
R
K
E
S
A
Chimpanzee
Pan troglodytes
XP_001142521
886
101061
K437
K
D
F
F
E
V
A
K
I
K
M
T
G
T
T
Rhesus Macaque
Macaca mulatta
XP_001087347
894
101935
T445
K
E
S
K
K
F
A
T
L
P
R
K
E
S
A
Dog
Lupus familis
XP_532380
894
102004
T445
K
E
S
K
K
F
A
T
L
P
R
K
E
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3S6
894
101859
T445
K
E
S
K
K
F
A
T
L
P
R
K
E
S
A
Rat
Rattus norvegicus
NP_001019941
681
76652
N278
S
E
I
E
F
L
V
N
H
M
D
L
A
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506171
894
101975
T445
K
E
S
K
K
F
A
T
L
P
R
K
E
S
A
Chicken
Gallus gallus
XP_001232097
895
102211
T445
K
E
G
K
K
F
A
T
L
P
R
K
E
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955891
892
101963
T446
D
G
K
G
K
F
A
T
L
P
R
K
E
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVG4
889
102677
L460
L
R
N
S
R
E
D
L
D
M
S
T
S
S
R
Honey Bee
Apis mellifera
XP_396967
859
98113
L419
S
K
L
Y
K
R
D
L
K
R
F
F
D
E
A
Nematode Worm
Caenorhab. elegans
Q20678
848
97279
I410
N
L
V
L
Q
K
Y
I
D
S
T
N
L
L
Y
Sea Urchin
Strong. purpuratus
XP_787291
869
100242
F427
E
R
E
L
K
D
F
F
E
R
A
R
Q
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SX85
887
100046
L460
A
Y
C
S
S
L
N
L
L
L
R
R
E
A
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
99.5
98.5
N.A.
97.1
70.9
N.A.
95
94
N.A.
84.6
N.A.
40.1
42
34.3
49.1
Protein Similarity:
100
98.2
100
98.8
N.A.
98.6
73.8
N.A.
97.1
96.6
N.A.
91.6
N.A.
62.4
62.5
54.5
68.7
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
100
93.3
N.A.
73.3
N.A.
6.6
13.3
0
6.6
P-Site Similarity:
100
40
100
100
N.A.
100
13.3
N.A.
100
93.3
N.A.
73.3
N.A.
20
26.6
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
58
0
0
0
8
0
8
15
58
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
8
15
0
15
0
8
0
8
0
0
% D
% Glu:
8
50
8
8
8
8
0
0
8
0
0
0
58
8
0
% E
% Phe:
0
0
8
8
8
50
8
8
0
0
8
8
0
0
0
% F
% Gly:
0
8
8
8
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
50
8
8
43
65
8
0
8
8
8
0
50
0
8
0
% K
% Leu:
8
8
8
15
0
15
0
22
58
8
0
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
15
8
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
8
8
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
15
0
0
8
8
0
0
0
15
58
15
0
0
15
% R
% Ser:
15
0
36
15
8
0
0
0
0
8
8
0
8
58
0
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
8
15
0
8
8
% T
% Val:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _